Can Sulfasalazine Cause Weight Loss

by Penny Alba


Does sulfasalazine cause weight gain? Sulfasalazine may cause kidney problems that lead to fluid build-up in your body and weight gain. You may have puffy eyes or swelling in your arms, ankles or feet, or little or no urination. Call your doctor right away if you have any of these side effects.

What are the most common side effects of sulfasalazine?

Common side effectsThe most common side effects of sulfasalazine are headache, nausea, fever, rash, and reversible infertility in men. Headache is one of the most common complaints, affecting up to one-third of people.

What is the problem with sulfasalazine?

You’ll need blood tests and liver and kidney tests before you start treatment with sulfasalazine, and then regular monitoring tests. The most common side effects of sulfasalazine are indigestion and feeling sick. Drink plenty of fluids when taking sulfasalazine to help prevent possible kidney problems.

Does sulfasalazine make you tired?

Sulfasalazine oral tablet may cause drowsiness. It may also cause other side effects.

Does sulfasalazine decrease appetite?

Loss of appetite, nausea, sensitivity to sunlight, and nervousness are also common when starting therapy. Sperm count may be reduced in men who take sulfasalazine, although this is reversible once the drug is stopped.

Which arthritis meds cause weight loss?

According to a 2016 study , people with RA who take the medication leflunomide (Arava) are more likely to experience weight loss. This medication is a disease-modifying antirheumatic drug.

What are the long term effects of taking sulfasalazine?

The most serious side effects of sulfasalazine are: Blood disorders, including anemia and low white blood cell counts. Liver poisoning. Kidney dysfunction.

When is the best time to take sulfasalazine?

It is best to take this medicine right after meals, at evenly spaced times throughout the day and night. Try not to let more than 8 hours go by between doses, even at night. Swallow the enteric-coated tablet whole. Do not crush, break, or chew it.

What medications should not be taken with sulfasalazine?

Some products that may interact with this drug include: digoxin, folic acid, methenamine, PABA taken by mouth. Sulfasalazine is very similar to mesalamine. Do not use mesalamine medications taken by mouth while using sulfasalazine.

Why is sulfasalazine being discontinued?

However, owing to adverse effects (allergy, dyspepsia), this drug often has to be withdrawn. The present work analyzes, in 704 patients with chronic inflammatory bowel disease, the frequency of such side effects that over a 15-year period necessitated withdrawal of sulfasalazine (Salazopyrin).


Most commonly reported side effects

Side effects that can occur will be experienced during the first three to six months. These include: Nausea (feeling sick), vomiting, dizziness, headache, diarrhoea, loss of appetite. Skin rash, raised temperature, insomnia, itching of skin, tinnitus.

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