Does Amitriptyline Cause Weight Loss

by Penny Alba


While most users report an increase in appetite, others may feel less hungry while taking the drug and experience amitriptyline and weight loss. Weight loss can be attributed to increased serotonin levels caused by Elavil-mediated serotonin reuptake inhibition.

Does everyone gain weight on amitriptyline?

Amitriptyline and Weight Gain: The Bottom Line

Although amitriptyline appears to cause a slight weight gain on average, it is not a significant amount. Most research shows only minor weight changes on par with or less than similar antidepressants.

What are the most common side effects of amitriptyline?

5. Side effects
dry mouth.
difficulty urinating.

Which antidepressants help you lose weight?

Most antidepressant drugs are most commonly associated with weight gain, but there are three that have been linked to weight loss: Bupropion (Wellbutrin) Fluoxetine (Prozac) Duloxetine (Cymbalta)

Why shouldn’t I take amitriptyline after 8 p.m.?

It has a sedative effect and can make you sleepy, so take it an hour or two before bedtime, but no later than 8:00 p.m.

How long should you take amitriptyline?

You may feel a little better after a week or two. But amitriptyline can take four to six weeks to work as a pain reliever. You will probably take it for as long as it improves your condition. Some people take it for several months or even years without any harmful effects.

Will 10 mg of amitriptyline cause weight gain?

Tricyclic antidepressants

Tricyclic antidepressants, also called cyclic antidepressants or ATCs, can cause weight gain. These drugs include: amitriptyline (Elavil)

Why would someone be prescribed amitriptyline?

Why is this drug prescribed? Amitriptyline is used to treat symptoms of depression. Amitriptyline belongs to a class of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance.

How does Amitriptyline 10mg make you feel?

The most common side effects of amitriptyline are: dizziness. dry mouth. constipation.

Why does amitriptyline make you fat?

Amitriptyline may affect your feelings of hunger. Some people feel hungrier when they take it, while others feel less hungry. Therefore, your weight may change when you start taking it. If you start having weight problems while taking amitriptyline, talk to your doctor or pharmacist.


Six weight-loss drugs have been approved by the United States Food and Drug Administration (FDA) for long-term use:
Bupropion-naltrexone (Contrave)
Liraglutide (Saxenda)
Orlistat (Xenical, Alli)
Phentermine-topiramate ( Qsymia)
Semaglutide (Wegovy)
Setmelanotide (Imcivree)

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